Many life sciences teams experience a false tradeoff between strict GMP compliance and operational speed. In practice, breakdowns usually originate in execution gaps such as slow handoffs, ambiguous ownership, manual evidence assembly, and inconsistent approval paths across MES, QMS, LIMS, and ERP. This article explains why adding documentation rarely fixes the underlying problem, and how an execution-first approach built on governed workflows, policy-based decisioning, standardized exceptions, verifiable closure, and telemetry can strengthen GMP compliance while reducing friction and cycle time.